Resident Evil Village is a first-person game, but aside from the perspective difference, it’s quite similar to the acclaimed Resident Evil 4, particularly in its setting and tone. Capcom is certainly aware of this, and it even included a silly reference to the earlier game that you could see when playing the recent demo.
The Duke’s Emporium is the cart you’ll visit in the game in order to purchase weapons and other items. The vendor doesn’t look anything like the one in Resident Evil 4, but he does use one of his lines as a joke. You’ll certainly be familiar with it if you played that game for any length of time.
“What’re ya buying?” he asks before laughing about how an “old friend” used to say this. It could just be a simple Easter egg for fans of the series, or it could be a hint at a connection between the games. Both are in Europe, but Resident Evil 4 is in Spain, meaning one of these vendors would have to have done some traveling in order to know the other.